Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208352 | 0.86 | HTR1D (0.40) | SLC6A4HTR2ASLC6A2SLC6A3HTR1B | |
| SCHEMBL774111 | 0.85 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3GPR84ALDH1A1 | |
| SCHEMBL9287650 | 0.85 | HTR1D (0.42) | SLC6A4HTR2AHTR2CSLC6A2SLC6A3 | |
| SCHEMBL1697454 | 0.85 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3GPR84ALDH1A1 | |
| SCHEMBL9287655 | 0.85 | HTR1D (0.42) | SLC6A4HTR2AHTR2CSLC6A2SLC6A3 | |
| SCHEMBL8209090 | 0.85 | SLC6A4 (0.50) | SLC6A4HTR2ASLC6A2SLC6A3GPR84 | |
| SCHEMBL774639 | 0.85 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3GPR84ALDH1A1 | |
| SCHEMBL8507358 | 0.85 | HTR1D (0.45) | SLC6A4HTR2ASLC6A2SLC6A3HTR1B | |
| SCHEMBL8506282 | 0.82 | HTR1D (0.44) | SLC6A4SLC6A2SLC6A3HTR1AHTR1B | |
| SCHEMBL8507170 | 0.82 | HTR1D (0.43) | SLC6A4SLC6A2SLC6A3HTR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100291-A | FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-08-08 | — | — | US | disclosed |