Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.54 |
| ▸ | EGFR | P00533 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3314469 | 0.91 | KMT2A (0.65) | KMT2AMEN1MAOAEGFRMAOB | |
| SCHEMBL3314426 | 0.84 | KMT2A (0.65) | KMT2AMEN1MAOAEGFRMAOB | |
| SCHEMBL3314624 | 0.83 | KMT2A (0.64) | KMT2AMEN1MAOAEGFRMAOB | |
| SCHEMBL3314397 | 0.79 | ALDH1A1 (0.62) | KMT2AMEN1MAOAEGFRMAOB | |
| SCHEMBL8206289 | 0.78 | ALDH1A1 (0.57) | KMT2AMEN1MAOAEGFRMAOB | |
| SCHEMBL3319431 | 0.76 | KMT2A (0.61) | KMT2AMEN1MAOAEGFRMAOB | |
| SCHEMBL3312868 | 0.76 | KMT2A (0.65) | KMT2AMEN1MAOAEGFRMAOB | |
| SCHEMBL3310619 | 0.76 | KDM4E (0.61) | KMT2AMEN1MAOAEGFRMAOB | |
| SCHEMBL13576145 | 0.73 | KMT2A (0.64) | KMT2AMEN1MAOAMAOB | |
| SCHEMBL3311114 | 0.73 | KMT2A (0.68) | KMT2AMEN1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045663-A2 | ARYL-SUBSTITUTED HETEROCYCLIC PDE4 INHIBITORS AS ANTIINFLAMMATORY AGENTS | KALYPSYS, INC. (US) | 2008-04-17 | — | — | WO | disclosed |