Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6219776 | 0.83 | LMNA (0.50) | LMNATDP1POLBKMT2AKDM4E | |
| SCHEMBL1231766 | 0.80 | LMNA (0.55) | LMNATDP1POLBKMT2AKDM4E | |
| SCHEMBL10530778 | 0.80 | LMNA (0.47) | LMNATDP1POLBKMT2AKDM4E | |
| SCHEMBL4049351 | 0.80 | LMNA (0.47) | LMNATDP1POLBKMT2AKDM4E | |
| SCHEMBL11686037 | 0.79 | LMNA (0.46) | LMNATDP1POLBKMT2AKDM4E | |
| SCHEMBL11681393 | 0.79 | LMNA (0.46) | LMNATDP1POLBKMT2AKDM4E | |
| SCHEMBL10530789 | 0.79 | LMNA (0.53) | LMNATDP1POLBKMT2AKDM4E | |
| SCHEMBL20553757 | 0.78 | LMNA (0.44) | LMNATDP1POLBKMT2AKDM4E | |
| SCHEMBL10494901 | 0.78 | LMNA (0.45) | LMNAPOLBTSHR | |
| SCHEMBL10494979 | 0.78 | LMNA (0.45) | LMNAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6024941-A | VITAMIN A AND STABILIZERS | SHISEIDO COMPANY, LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| US-5484816-A | STABILIZED VITAMIN A COMPOSITION | SHISEIDO COMPANY, LTD. (JP) | 1996-01-16 | — | — | US | disclosed |