SCHEMBL820869

SCHEMBL820869

C=C(C)C(=O)Oc1cccc(C(=O)c2ccccc2)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.57
MAPT P10636 5/20 0.50
KDM4E B2RXH2 4/20 0.50
HSD17B10 Q99714 4/20 0.50
MAPK1 P28482 3/20 0.50
ALOX15 P16050 1/20 0.50
HPGD P15428 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALDH1A1 P00352 1/20 0.45
ESR1 P03372 1/20 0.45
ITGB3 P05106 1/20 0.45
ITGA2B P08514 1/20 0.45
HMGB1 P09429 1/20 0.45
TSHR P16473 1/20 0.45
GGT1 P19440 1/20 0.45
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
BLM P54132 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
LMNA P02545 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28628528 0.88 MAPT (0.66) ELANEMAPTKDM4EHSD17B10MAPK1
SCHEMBL29670258 0.88 ELANE (0.64) ELANEMAPTKDM4EHSD17B10MAPK1
SCHEMBL474811 0.88 ELANE (0.64) ELANEMAPTKDM4EHSD17B10MAPK1
SCHEMBL10662113 0.85 ELANE (0.57) ELANEMAPTKDM4EHSD17B10MAPK1
SCHEMBL8989321 0.83 MAPT (0.43) ELANEMAPTKDM4EHSD17B10MAPK1
SCHEMBL15496050 0.83 KMT2A (0.43) ELANEMAPTKDM4EHSD17B10MAPK1
SCHEMBL9851284 0.82 MAPT (0.46) ELANEMAPTKDM4EHSD17B10MAPK1
SCHEMBL5506364 0.82 ELANE (0.57) ELANEMAPTKDM4EHSD17B10MAPK1
SCHEMBL28273804 0.82 TDP1 (0.49) ELANEMAPTKDM4EHSD17B10MAPK1
SCHEMBL6928775 0.81 ELANE (0.56) ELANEMAPTKDM4EHSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111201253-B Vinyl chloride-based resin composition and method for preparing the same 韩华思路信(株) 2022-05-24 CN claimed
US-10829710-B2 Slipperiness-imparting agent and slipperiness-imparting method NOF CORPORATION (JP) 2020-11-10 US claimed
CN-111201253-A Vinyl chloride-based resin composition and method for preparing the same 韩华思路信(株) 2020-05-26 CN claimed
US-20160194424-A1 MONOMERS FOR USE IN A POLYMERIZABLE COMPOSITION AND HIGH REFRACTIVE INDEX POLYMER FOR OPTHALMIC APPLICATIONS CONTAMAC LIMITED (GB) 2016-07-07 US claimed
US-20080031918-A1 BARRIERS FOR POLYMERIC COATINGS SURMODICS, INC. 2008-02-07 US claimed
EP-1567203-B1 BARRIERS FOR BIOACTIVE AGENT-CONTAINING POLYMERIC COATINGS SURMODICS INC (US) 2007-09-26 EP claimed
JP-3954616-B2 2007-08-08 JP claimed
US-7097850-B2 Bioactive agent release coating and controlled humidity method SURMODICS, INC. (US) 2006-08-29 US claimed
EP-1551469-B1 BIOACTIVE AGENT RELEASE COATING WITH AROMATIC POLY(METH)ACRYLATES SURMODICS INC (US) 2006-03-08 EP claimed
JP-2006505303-A 2006-02-16 JP claimed
US-20040111144-A1 Barriers for polymeric coatings Surmodics Coatings, LLC 2004-06-10 US claimed
WO-2003105920-A1 METHOD AND SYSTEM FOR PROVIDING BIOACTIVE AGENT RELEASE COATING SURMODICS, INC. (US) 2003-12-24 WO claimed
WO-2003105918-A1 BIOACTIVE AGENT RELEASE COATING WITH AROMATIC POLY(METH)ACRYLATES SURMODICS, INC. (US) 2003-12-24 WO claimed
WO-2003105919-A1 BIOACTIVE AGENT RELEASE COATING AND CONTROLLED HUMIDITY METHOD SURMODICS, INC. (US) 2003-12-24 WO claimed
US-20030232087-A1 Bioactive agent release coating with aromatic poly(meth)acrylates Surmodics Coatings, LLC 2003-12-18 US claimed
US-20030232122-A1 Bioactive agent release coating and controlled humidity method Surmodics Coatings, LLC 2003-12-18 US claimed
US-20020188037-A1 Method and system for providing bioactive agent release coating Surmodics Coatings, LLC 2002-12-12 US claimed
EP-0869138-B1 NOVEL COPOLYMERS FORMED FROM THREE COMPONENTS AND INTRAOCULAR LENSES MADE THEREOF SANTEN PHARMACEUTICAL CO LTD (JP) 2002-08-07 EP claimed
US-6132462-A HYDROXYALKYL (ALKYL)ACRYLATE; PYRROLIDONE-CONTAINING ACRYLIC ESTER, AMIDE, OR IMIDE; AND A LOWER ALKYL (ALKYL)ACRYLATE TERPOLYMER; FOLDABLE LENSE HAVING GIVEN REFRACTIVE INDEX, RECOVERY SPEED FROM FOLD STATE AND TENSILE STRENGTH SANTEN PHARMACEUTICAL CO., LTD. (JP) 2000-10-17 US claimed
EP-0869138-A1 NOVEL COPOLYMERS FORMED FROM THREE COMPONENTS AND INTRAOCULAR LENSES MADE THEREOF SANTEN PHARMACEUTICAL CO., LTD. (JP) 1998-10-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160194424-A1 MONOMERS FOR USE IN A POLYMERIZABLE COMPOSITION AND HIGH REFRACTIVE INDEX POLYMER FOR OPTHALMIC APPLICATIONS NR2E3, NR1I2, NR1I3 ELANE 2093/4885MAPT 2463/4885KDM4E 4759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.