Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662113 | 0.87 | ELANE (0.57) | ELANEMAPTHPGDHSD17B10MAPK1 | |
| Benzoic Acid SCHEMBL10793762 | 0.84 | ELANE (0.53) | ELANEMAPTHSD17B10LMNAALDH1A1 | |
| SCHEMBL15495801 | 0.83 | THRB (0.41) | ELANEMAOAMAOBMAPTHPGD | |
| SCHEMBL820869 | 0.81 | ELANE (0.57) | ELANEMAPTHPGDHSD17B10MAPK1 | |
| SCHEMBL10407840 | 0.81 | ELANE (0.46) | ELANEMAOAMAOBMAPTHPGD | |
| SCHEMBL1415831 | 0.81 | TDP1 (0.46) | ELANEMAOAMAOBLIG1MAPT | |
| SCHEMBL474811 | 0.80 | ELANE (0.64) | ELANEMAPTHPGDHSD17B10MAPK1 | |
| SCHEMBL29670258 | 0.80 | ELANE (0.64) | ELANEMAPTHPGDHSD17B10MAPK1 | |
| SCHEMBL5065272 | 0.80 | ELANE (0.47) | ELANEMAPTHPGDHSD17B10MAPK1 | |
| SCHEMBL15495958 | 0.79 | LMNA (0.53) | ELANEMAPTHPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216142-A4 | THERMOFORMABLE OPHTHALMIC LENS | NOVARTIS AG (CH) | 2003-06-11 | — | — | EP | disclosed |
| EP-1216142-A1 | THERMOFORMABLE OPHTHALMIC LENS | Wesley Jessen Corporation (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001005578-A1 | THERMOFORMABLE OPHTHALMIC LENS | WESLEY-JESSEN CORPORATION (US) | 2001-01-25 | — | — | WO | disclosed |