Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 10/20 | 0.64 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.54 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434519 | 0.81 | PNP (0.64) | PNPFGFR1FGFR2 | |
| SCHEMBL3300185 | 0.81 | PNP (0.64) | PNPFGFR1FGFR2 | |
| SCHEMBL4963414 | 0.81 | PNP (0.64) | PNPFGFR1FGFR2 | |
| SCHEMBL18248 | 0.79 | PNP (1.00) | PNPFGFR1FGFR2 | |
| SCHEMBL4966173 | 0.78 | PNP (0.63) | PNPFGFR1FGFR2CYP2A6 | |
| SCHEMBL4962855 | 0.77 | PNP (1.00) | PNPFGFR1FGFR2 | |
| Hydrochloric Acid SCHEMBL17186372 | 0.76 | PNP (0.97) | PNPFGFR1FGFR2 | |
| SCHEMBL9960811 | 0.75 | PNP (0.71) | PNPFGFR1FGFR2 | |
| SCHEMBL1938287 | 0.74 | PNP (0.71) | PNPFGFR1FGFR2 | |
| SCHEMBL9283418 | 0.73 | PNP (0.66) | PNPFGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096724-A | O(6)-ALKYLGUANINE-DNA ALKYLTRANSFERASE (ATASE) ENZYME INHIBITORS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-08-01 | — | — | US | disclosed |