Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794185 | 0.94 | ALOX15 (0.40) | TSHRALOX15ALDH1A1CYP3A4USP2 | |
| SCHEMBL28249306 | 0.86 | TSHR (0.42) | TSHRPLA2G2CALOX15ALDH1A1CYP3A4 | |
| Undecanal SCHEMBL8210493 | 0.85 | TSHR (0.53) | TSHRFAAHTRPV1PLA2G2CALDH1A1 | |
| Tetradecanal SCHEMBL6162330 | 0.77 | TSHR (0.64) | TSHRFAAHTRPV1ALDH1A1MAPT | |
| Dodecanal SCHEMBL14331913 | 0.77 | TSHR (0.64) | TSHRFAAHTRPV1ALDH1A1MAPT | |
| Decanal SCHEMBL10437525 | 0.77 | TSHR (0.64) | TSHRFAAHTRPV1ALDH1A1MAPT | |
| Palmitaldehyde SCHEMBL10437527 | 0.77 | TSHR (0.64) | TSHRFAAHTRPV1ALDH1A1MAPT | |
| Nonanal SCHEMBL4634233 | 0.77 | TSHR (0.64) | TSHRFAAHTRPV1ALDH1A1MAPT | |
| Undecanal SCHEMBL5388011 | 0.77 | TSHR (0.64) | TSHRFAAHTRPV1ALDH1A1MAPT | |
| Heptanal SCHEMBL7746289 | 0.77 | TSHR (0.64) | TSHRFAAHTRPV1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053223-A1 | SERINE CARBONATES | Givaudan SA (CH) | 2000-11-22 | — | — | EP | disclosed |
| WO-2000034232-A1 | SERINE CARBONATES | GIVAUDAN SA (CH) | 2000-06-15 | — | — | WO | disclosed |