Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.65 |
| ▸ | DRD4 | P21917 | 4/20 | 0.65 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.57 |
| ▸ | BIRC2 | Q13490 | 5/20 | 0.49 |
| ▸ | AKT1 | P31749 | 4/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7553491 | 0.79 | DRD2 (0.83) | DRD2DRD4NOTUM | |
| SCHEMBL7552763 | 0.79 | DRD4 (1.00) | DRD2DRD4 | |
| SCHEMBL7551427 | 0.79 | DRD2 (0.83) | DRD2DRD4NOTUM | |
| SCHEMBL7558681 | 0.78 | DRD4 (0.81) | DRD2DRD4NOTUM | |
| SCHEMBL7555333 | 0.77 | DRD2 (0.78) | DRD2DRD4NOTUM | |
| SCHEMBL7555293 | 0.77 | DRD4 (0.82) | DRD2DRD4NOTUM | |
| SCHEMBL7550236 | 0.76 | NOTUM (0.69) | DRD2DRD4NOTUMAKT1PIK3CD | |
| SCHEMBL7555846 | 0.76 | DRD2 (0.77) | DRD2DRD4NOTUM | |
| SCHEMBL20957045 | 0.74 | MAPK1 (0.63) | DRD2DRD4NOTUM | |
| SCHEMBL14294095 | 0.74 | NOTUM (1.00) | DRD2DRD4NOTUMAKT1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000076967-A1 | BENZYLPIPERAZINYL-INDOLINYLETHANONES | NEUROGEN CORPORATION (US) | 2000-12-21 | — | — | WO | disclosed |