Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 14/20 | 0.59 |
| ▸ | HCRTR1 | O43613 | 12/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13208901 | 0.85 | POLB (0.58) | HCRTR2HCRTR1LMNAMAPTPOLB | |
| SCHEMBL13789995 | 0.85 | HCRTR1 (0.51) | HCRTR2HCRTR1 | |
| SCHEMBL2905303 | 0.85 | HCRTR1 (0.51) | HCRTR2HCRTR1 | |
| SCHEMBL2904616 | 0.85 | HCRTR1 (0.51) | HCRTR2HCRTR1 | |
| SCHEMBL17501812 | 0.85 | HCRTR2 (0.65) | HCRTR2HCRTR1 | |
| SCHEMBL19894076 | 0.85 | HCRTR2 (0.48) | HCRTR2HCRTR1LMNAMAPT | |
| SCHEMBL17539230 | 0.84 | HCRTR2 (0.56) | HCRTR2HCRTR1 | |
| SCHEMBL17539260 | 0.84 | HCRTR2 (0.56) | HCRTR2HCRTR1 | |
| SCHEMBL2358754 | 0.84 | HCRTR2 (0.64) | HCRTR2HCRTR1 | |
| SCHEMBL17539262 | 0.84 | HCRTR2 (0.64) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020403-A1 | PREPARATION OF A BENZOIC ACID DERIVATIVE AND ITS USE FOR THE PREPARATION OF SUVOREXANT | SANDOZ AG (CH) | 2016-02-11 | — | — | WO | disclosed |
| WO-2016020403-A1 | PREPARATION OF A BENZOIC ACID DERIVATIVE AND ITS USE FOR THE PREPARATION OF SUVOREXANT | SANDOZ AG (CH) | 2016-02-11 | — | — | WO | disclosed |
| WO-2008008518-A1 | SUBSTITUTED DIAZEPAN OREXIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2008-01-17 | — | — | WO | disclosed |