Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17539262 | 1.00 | HCRTR2 (0.64) | HCRTR2HCRTR1 | |
| SCHEMBL17501812 | 0.99 | HCRTR2 (0.65) | HCRTR2HCRTR1 | |
| SCHEMBL23018148 | 0.87 | HCRTR2 (0.58) | HCRTR2HCRTR1 | |
| SCHEMBL2356095 | 0.86 | HCRTR2 (0.58) | HCRTR2HCRTR1 | |
| SCHEMBL21443716 | 0.84 | HCRTR2 (0.60) | HCRTR2HCRTR1 | |
| SCHEMBL8209215 | 0.84 | HCRTR2 (0.59) | HCRTR2HCRTR1 | |
| SCHEMBL13106337 | 0.83 | HCRTR1 (0.61) | HCRTR2HCRTR1 | |
| SCHEMBL13733737 | 0.82 | HCRTR2 (0.49) | HCRTR2HCRTR1 | |
| SCHEMBL17502930 | 0.81 | HCRTR2 (0.52) | HCRTR2HCRTR1 | |
| SCHEMBL7911862 | 0.81 | HCRTR2 (0.67) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350066-A1 | 2,5-DISUBSTITUTED PIPERIDINE OREXIN RECEPTOR ANTAGONISTS | Merck Sharp & Dohme Corp. (US) | 2011-08-03 | — | — | EP | claimed |