Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11310616 | 0.90 | HTT (0.52) | HTTFOLH1DPP8DPP7LMNA | |
| SCHEMBL11294170 | 0.90 | HTT (0.52) | HTTFOLH1DPP8DPP7LMNA | |
| SCHEMBL11048769 | 0.90 | HTT (0.52) | HTTFOLH1DPP8DPP7LMNA | |
| SCHEMBL8613001 | 0.88 | FOLH1 (0.52) | HTTFOLH1DPP8DPP7TGM2 | |
| SCHEMBL12727090 | 0.86 | FOLH1 (0.54) | HTTFOLH1DPP8DPP7TGM2 | |
| SCHEMBL2138925 | 0.85 | LMNA (0.50) | HTTFOLH1DPP8DPP7LMNA | |
| SCHEMBL3462691 | 0.85 | LMNA (0.50) | HTTFOLH1DPP8DPP7LMNA | |
| SCHEMBL11291906 | 0.85 | LMNA (0.50) | HTTFOLH1DPP8DPP7LMNA | |
| SCHEMBL18337922 | 0.85 | FOLH1 (0.56) | FOLH1DPP8DPP7TGM2MMP2 | |
| SCHEMBL9976419 | 0.85 | FOLH1 (0.56) | FOLH1DPP8DPP7TGM2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057419-A | DRUGS AND IMAGES | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |