Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958118 | 0.87 | REN (0.75) | REN | |
| SCHEMBL6950956 | 0.83 | REN (0.56) | REN | |
| SCHEMBL7540900 | 0.83 | REN (0.60) | REN | |
| SCHEMBL6042327 | 0.82 | REN (0.58) | REN | |
| SCHEMBL7081616 | 0.82 | REN (0.71) | REN | |
| SCHEMBL6955494 | 0.82 | REN (0.68) | REN | |
| SCHEMBL6041452 | 0.82 | REN (0.80) | REN | |
| SCHEMBL6042048 | 0.81 | REN (0.71) | REN | |
| Hydrochloric Acid SCHEMBL6041926 | 0.81 | REN (0.67) | REN | |
| Bicarbonate SCHEMBL7547243 | 0.81 | REN (0.63) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150526-A | Piperidine derivative having renin inhibiting activity | HOFFMANN-LA ROCHE INC. (US) | 2000-11-21 | — | — | US | disclosed |