Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8196332 | 0.89 | REN (0.66) | REN | |
| Trifluoroacetic Acid SCHEMBL8204725 | 0.88 | REN (0.62) | REN | |
| Hydrochloric Acid SCHEMBL7581701 | 0.86 | REN (0.66) | REN | |
| Trifluoroacetic Acid SCHEMBL6041509 | 0.85 | REN (0.64) | REN | |
| Trifluoroacetic Acid SCHEMBL7562485 | 0.84 | REN (0.64) | REN | |
| Trifluoroacetic Acid SCHEMBL7561476 | 0.83 | REN (0.67) | REN | |
| Trifluoroacetic Acid SCHEMBL7562814 | 0.83 | REN (0.61) | REN | |
| Trifluoroacetic Acid SCHEMBL8207430 | 0.83 | REN (0.64) | REN | |
| Hydrochloric Acid SCHEMBL8209527 | 0.82 | REN (0.85) | REN | |
| Trifluoroacetic Acid SCHEMBL7562840 | 0.82 | REN (0.74) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150526-A | Piperidine derivative having renin inhibiting activity | HOFFMANN-LA ROCHE INC. (US) | 2000-11-21 | — | — | US | disclosed |