Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 18/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068597 | 0.88 | PSMB8 (0.50) | — | |
| SCHEMBL3066926 | 0.87 | CHRM3 (0.42) | CHRM3 | |
| SCHEMBL3074978 | 0.85 | HRH3 (0.48) | CHEK1 | |
| SCHEMBL3074161 | 0.85 | HRH3 (0.48) | CHEK1 | |
| SCHEMBL3066747 | 0.84 | CHKA (0.46) | CHRM3 | |
| SCHEMBL3076811 | 0.84 | CHKA (0.46) | CHRM3 | |
| SCHEMBL3057816 | 0.81 | HCRTR1 (0.44) | — | |
| SCHEMBL3070124 | 0.81 | TACR2 (0.44) | — | |
| SCHEMBL3070726 | 0.80 | CXCR4 (0.43) | — | |
| SCHEMBL3067798 | 0.80 | DRD2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008032191-A2 | SPIRO-OXAZOLIDINONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS | ASTRAZENECA AB (US) | 2008-03-20 | — | — | WO | disclosed |