Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329512 | 0.94 | LPAR3 (0.39) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7189533 | 0.91 | MEN1 (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL8705724 | 0.89 | TSHR (0.42) | THRBTSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL15673463 | 0.89 | MEN1 (0.52) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9483196 | 0.87 | MEN1 (0.54) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL3631091 | 0.87 | TSHR (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL4921495 | 0.87 | MEN1 (0.54) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL983239 | 0.87 | MEN1 (0.54) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7181564 | 0.87 | MEN1 (0.54) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL482556 | 0.86 | TSHR (0.35) | TSHRCYP3A4LPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6149837-A | SUBSTITUTED 1,4-BIS(SUBSTITUED PHENYLACETYLENE)BENZENE WHERE AT LEAST ONE RING HAS AN ALKYL ATTACHMENT, HAS A LARGE ANISOTROPY OF REFRACTIVE INDEX, TENDS TO BE MIXED WITH OTHER LIQUID CRYSTALS, IS LIGHT STABLE; LIQUID CRYSTAL ELEMENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-11-21 | — | — | US | disclosed |