Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202227 | 0.90 | GRM2 (0.39) | GRM2MLNRTACR2TACR1AGTR1 | |
| SCHEMBL3057908 | 0.81 | GRM2 (0.53) | GRM2TACR2TACR1 | |
| SCHEMBL3081725 | 0.80 | GRM2 (0.47) | GRM2TACR2TACR1 | |
| SCHEMBL3068893 | 0.80 | GRM2 (0.44) | GRM2TACR2TACR1 | |
| SCHEMBL3070726 | 0.80 | CXCR4 (0.43) | GRM2MLNRTACR2TACR1 | |
| SCHEMBL3067246 | 0.80 | ITGB1 (0.43) | GRM2TACR2TACR1 | |
| SCHEMBL3068774 | 0.78 | GRM2 (0.47) | GRM2MLNRTACR2TACR1AGTR1 | |
| SCHEMBL3073111 | 0.78 | GRM2 (0.50) | GRM2TACR2TACR1 | |
| SCHEMBL3068599 | 0.76 | GRM2 (0.49) | GRM2MLNRTACR2TACR1 | |
| SCHEMBL13140370 | 0.75 | GRM2 (0.51) | GRM2TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008032191-A2 | SPIRO-OXAZOLIDINONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS | ASTRAZENECA AB (US) | 2008-03-20 | — | — | WO | disclosed |