SCHEMBL8209907 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	AQP1	P29972	3/20	0.49

▸	PRKAB2	O43741	2/20	0.37

▸	PRKAG1	P54619	2/20	0.37

▸	PRKAA2	P54646	2/20	0.37

▸	PRKAA1	Q13131	2/20	0.37

▸	PRKAG3	Q9UGI9	2/20	0.37

▸	PRKAG2	Q9UGJ0	2/20	0.37

▸	PRKAB1	Q9Y478	2/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8203901	0.93	AQP1 (0.53)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL8212155	0.91	AQP1 (0.58)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL8209712	0.88	AQP1 (0.49)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL8248458	0.88	AQP1 (0.63)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL4623042	0.87	AQP1 (0.60)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL8257872	0.87	AQP1 (0.60)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL4623038	0.87	AQP1 (0.60)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL8202522	0.86	AQP1 (0.48)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL8212157	0.86	AQP1 (0.47)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL8202627	0.86	AQP1 (0.46)	AQP1PRKAB2PRKAG1PRKAA2PRKAA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008052087-A1	CHROMANE DERIVATIVES AND USES THEREOF	WYETH (US)	2008-05-02	—	—	WO	disclosed