Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 11/20 | 0.67 |
| ▸ | SLC6A5 | Q9Y345 | 8/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | GPR139 | Q6DWJ6 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004224 | 0.87 | SLC6A9 (0.71) | SLC6A9SLC6A5CYP2D6CYP2C9GPR139 | |
| SCHEMBL2013856 | 0.85 | SLC6A9 (0.72) | SLC6A9SLC6A5CYP2D6CYP2C9GPR139 | |
| SCHEMBL2011796 | 0.81 | SLC6A9 (0.63) | SLC6A9SLC6A5CYP2D6CYP2C9GPR139 | |
| SCHEMBL2013066 | 0.81 | SLC6A9 (0.72) | SLC6A9SLC6A5CYP2D6CYP2C9GPR139 | |
| SCHEMBL2011215 | 0.81 | SLC6A9 (0.72) | SLC6A9SLC6A5CYP2D6CYP2C9GPR139 | |
| SCHEMBL2010042 | 0.81 | SLC6A9 (0.68) | SLC6A9SLC6A5CYP2D6CYP2C9GPR139 | |
| SCHEMBL2009331 | 0.80 | SLC6A9 (1.00) | SLC6A9SLC6A5CYP2D6CYP2C9GPR139 | |
| SCHEMBL2009334 | 0.80 | SLC6A9 (1.00) | SLC6A9SLC6A5CYP2D6CYP2C9GPR139 | |
| SCHEMBL12572421 | 0.80 | SLC6A9 (1.00) | SLC6A9SLC6A5CYP2D6CYP2C9GPR139 | |
| SCHEMBL2010557 | 0.80 | SLC6A9 (1.00) | SLC6A9SLC6A5CYP2D6CYP2C9GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022938-A1 | DI-AROMATIC SUBSTITUTED AMIDES AS INHIBITORS FOR GLYT1 | F. HOFFMANN-LA ROCHE AG (CH) | 2008-02-28 | — | — | WO | disclosed |