Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.51 |
| ▸ | LIPE | Q05469 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423931 | 0.87 | KMT2A (0.58) | MEN1KMT2AEPHX2LIPENPC1 | |
| SCHEMBL29460579 | 0.84 | MEN1 (0.62) | MEN1KMT2AEPHX2NPC1PKM | |
| SCHEMBL8218305 | 0.83 | SCN9A (0.47) | MEN1KMT2AEPHX2LIPEPKM | |
| SCHEMBL20456429 | 0.83 | USP2 (0.65) | MEN1KMT2AEPHX2LMNASMN1; SMN2 | |
| SCHEMBL4413446 | 0.82 | MEN1 (0.48) | MEN1KMT2AEPHX2LIPENPC1 | |
| SCHEMBL27848166 | 0.82 | MEN1 (0.55) | MEN1KMT2AEPHX2LIPENPC1 | |
| SCHEMBL2291403 | 0.82 | GAA (0.61) | MEN1KMT2AEPHX2LIPENPC1 | |
| SCHEMBL2297132 | 0.81 | MEN1 (0.54) | MEN1KMT2AEPHX2LIPENPC1 | |
| SCHEMBL309646 | 0.81 | MAPT (0.58) | MEN1KMT2AEPHX2LIPENPC1 | |
| SCHEMBL28485534 | 0.81 | LMNA (0.69) | MEN1KMT2AEPHX2PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |