Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MMP3 | P08254 | 14/20 | 0.60 |
| ▸ | MMP1 | P03956 | 13/20 | 0.60 |
| ▸ | MMP7 | P09237 | 9/20 | 0.60 |
| ▸ | MMP9 | P14780 | 2/20 | 0.60 |
| ▸ | MMP2 | P08253 | 8/20 | 0.59 |
| ▸ | MMP13 | P45452 | 9/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210485 | 1.00 | CA12 (0.61) | CA12CA1CA2CA9POLB | |
| SCHEMBL8498279 | 0.88 | MMP1 (0.62) | POLBMMP3MMP1MMP7MMP9 | |
| SCHEMBL8144145 | 0.88 | MMP1 (0.62) | POLBMMP3MMP1MMP7MMP9 | |
| SCHEMBL31630158 | 0.86 | CA12 (0.60) | CA12CA1CA2CA9MMP3 | |
| SCHEMBL8206200 | 0.86 | CA12 (0.60) | CA12CA1CA2CA9MMP3 | |
| SCHEMBL11458196 | 0.85 | POLB (0.58) | CA12CA1CA2CA9POLB | |
| SCHEMBL9379038 | 0.85 | POLB (0.58) | CA12CA1CA2CA9POLB | |
| SCHEMBL9215368 | 0.85 | POLB (0.58) | CA12CA1CA2CA9POLB | |
| SCHEMBL9215362 | 0.85 | POLB (0.58) | CA12CA1CA2CA9POLB | |
| SCHEMBL21551179 | 0.85 | POLB (0.58) | CA12CA1CA2CA9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121272-A | Bidentate metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |