Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210866 | 1.00 | NR4A1 (0.48) | NR4A1ARIDO1TDO2HNF4A | |
| SCHEMBL5568717 | 0.83 | KDM4E (0.41) | NR4A1ARKMT2ATP53CYP1A2 | |
| SCHEMBL5568373 | 0.82 | AR (0.38) | NR4A1ARMEN1KMT2ATP53 | |
| Trifluoroacetic Acid SCHEMBL5568550 | 0.80 | KDM4E (0.37) | NR4A1ARMEN1KMT2ATP53 | |
| SCHEMBL5569458 | 0.78 | IDO1 (0.46) | NR4A1ARIDO1 | |
| SCHEMBL13856251 | 0.65 | NR4A1 (1.00) | NR4A1ARMEN1KMT2AALDH1A1 | |
| SCHEMBL10747088 | 0.62 | TP53 (0.45) | ARMEN1KMT2ATP53CYP1A2 | |
| SCHEMBL27749589 | 0.60 | TDP1 (0.45) | NR4A1MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL4417724 | 0.60 | NR4A1 (0.40) | NR4A1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL1542926 | 0.59 | MAPT (0.48) | NR4A1ARMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042288-A1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033801-A1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1999-07-08 | — | — | WO | disclosed |