Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 9/20 | 0.45 |
| ▸ | CTSS | P25774 | 7/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568280 | 0.92 | CTSK (0.42) | IDO1CTSKCTSSNR4A1CTSB | |
| SCHEMBL29401990 | 0.68 | CTSS (0.76) | CTSKCTSSCTSLPPARAPPARG | |
| SCHEMBL613640 | 0.68 | CTSS (0.76) | CTSKCTSSCTSLPPARAPPARG | |
| SCHEMBL4122289 | 0.68 | CTSS (0.76) | CTSKCTSSCTSLPPARAPPARG | |
| SCHEMBL4600435 | 0.68 | CTSS (0.76) | CTSKCTSSCTSLPPARAPPARG | |
| Trifluoroacetic Acid SCHEMBL5563692 | 0.68 | AR (0.35) | NR4A1AR | |
| SCHEMBL834063 | 0.66 | PPARA (0.54) | CTSKCTSSCTSBCTSLPPARA | |
| SCHEMBL834064 | 0.66 | PPARA (0.54) | CTSKCTSSCTSBCTSLPPARA | |
| SCHEMBL345085 | 0.66 | CTSK (0.65) | IDO1CTSKCTSSPPARAPPARG | |
| SCHEMBL7288479 | 0.66 | CTSK (0.65) | IDO1CTSKCTSSPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042288-B1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INST NAT SANTE RECH MED (FR) | 2007-11-07 | — | — | EP | disclosed |
| US-6335360-B1 | INDOLINE-2-CARBOXYLIC AMIDE DERIVATIVES; OBESITY, EATING AND PSYCHOLOGICAL DISORDERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-01-01 | — | — | US | disclosed |
| EP-1042288-A1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033801-A1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1999-07-08 | — | — | WO | disclosed |