Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | MGAM | O43451 | 4/20 | 0.59 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.59 |
| ▸ | SI | P14410 | 4/20 | 0.59 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | F2 | P00734 | 2/20 | 0.59 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819737 | 0.89 | CYP4Z1 (0.61) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL6814131 | 0.89 | CYP4Z1 (0.61) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL17814919 | 0.86 | KMT2A (0.60) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL3120377 | 0.84 | ASAH1 (0.60) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL535388 | 0.84 | KMT2A (0.59) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL2489579 | 0.84 | KMT2A (0.55) | EGLN3GAAMGAMAMY1ASI | |
| Malonic Acid SCHEMBL8211367 | 0.82 | GAA (0.61) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL23780256 | 0.81 | KMT2A (0.62) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL3130159 | 0.81 | GAA (0.59) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL3252264 | 0.80 | HPGD (0.61) | EGLN3GAAMGAMAMY1ASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829586-B2 | Aryl-substituted nitrogen-containing heterocyclic compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20090275617-A1 | Aryl-Substituted Nitrogen-Containing Heterocyclic Compounds | MSD K.K. (JP) | 2009-11-05 | — | — | US | disclosed |
| EP-1935881-A1 | ARYL-SUBSTITUTED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275617-A1 | Aryl-Substituted Nitrogen-Containing Heterocyclic Compounds | OPRL1, NPSR1, NPBWR1 | EGLN3 656/4885GAA 3764/4885MGAM 4832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.