SCHEMBL8211375

SCHEMBL8211375

[CH2]CCCC(=C)CCCC

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.39
CES2 O00748 5/20 0.39
ALDH1A1 P00352 3/20 0.36
TP53 P04637 1/20 0.36
CA1 P00915 1/20 0.35
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
AKR1B1 P15121 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8217341 0.92 CES1 (0.38) CES1CES2ALDH1A1TP53CA1
SCHEMBL8220850 0.92 CES2 (0.42) CES1CES2ALDH1A1TSHRAKR1B1
SCHEMBL8209360 0.90 CES2 (0.44) CES1CES2ALDH1A1TSHRTHRB
SCHEMBL8220801 0.90 CES2 (0.39) CES1CES2ALDH1A1TSHR
SCHEMBL8218868 0.90 CES2 (0.44) CES1CES2ALDH1A1TSHRTHRB
SCHEMBL23925227 0.90 CES2 (0.39) CES1CES2ALDH1A1TSHR
SCHEMBL8218093 0.90 CES2 (0.39) CES1CES2ALDH1A1TSHR
SCHEMBL6990350 0.90 CES2 (0.44) CES1CES2ALDH1A1TSHRTHRB
SCHEMBL8220181 0.90 CES2 (0.44) CES1CES2ALDH1A1TSHRTHRB
SCHEMBL8216992 0.90 CES2 (0.44) CES1CES2ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105566680-B water-soluble antioxidant and preparation method thereof 品青企业股份有限公司 2018-03-27 CN disclosed
US-6143198-A SUITABLE FOR USE AS ELECTRO-OPTICAL DISPLAY MATERIALS; LIQUID CRYSTALLINE COMPOUND HAVING A LARGE ELASTIC CONSTANT RATIO, EXCELLENT COMPATIBILITY WITH OTHER LIQUID CRYSTALLINE COMPOUND, AND LOW TEMPERATURE CHEMICAL STABILITY CHISSO CORPORATION (JP) 2000-11-07 US disclosed
EP-0828700-A1 LIQUID CRYSTALLINE COMPOUNDS HAVING EXO-METHYLENE SITE AND LIQUID CRYSTAL COMPOSITIONS COMPRISING THE SAME CHISSO CORPORATION (JP) 1998-03-18 EP disclosed
WO-1996037451-A1 LIQUID CRYSTALLINE COMPOUNDS HAVING EXO-METHYLENE SITE AND LIQUID CRYSTAL COMPOSITIONS COMPRISING THE SAME CHISSO CORPORATION (JP) 1996-11-28 WO disclosed