Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4162790 | 0.87 | KDM1A (0.34) | KDM1ABCHE | |
| SCHEMBL4167513 | 0.84 | MEN1 (0.34) | — | |
| SCHEMBL5041740 | 0.84 | MEN1 (0.35) | KDM1A | |
| SCHEMBL8933396 | 0.79 | KCNA5 (0.41) | — | |
| SCHEMBL4165486 | 0.78 | KDM1A (0.35) | KDM1ABCHE | |
| SCHEMBL8933586 | 0.77 | KCNA5 (0.41) | — | |
| SCHEMBL4173647 | 0.75 | — | — | |
| SCHEMBL19158282 | 0.73 | KDM1A (0.34) | KDM1A | |
| SCHEMBL8933626 | 0.73 | MEN1 (0.40) | — | |
| SCHEMBL19158191 | 0.72 | BRD4 (0.32) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188271-B2 | Polycyclic carbamoylpyridone derivative having HIV integrase inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2012-05-29 | — | — | US | disclosed |