⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8213075 | 1.00 | — | — | |
| SCHEMBL13577533 | 1.00 | — | — | |
| SCHEMBL12514893 | 0.79 | — | — | |
| SCHEMBL13640858 | 0.79 | — | — | |
| SCHEMBL13577575 | 0.79 | — | — | |
| SCHEMBL8214358 | 0.77 | — | — | |
| SCHEMBL14050301 | 0.77 | TGFBR1 (0.50) | — | |
| SCHEMBL77750 | 0.76 | — | — | |
| SCHEMBL5132096 | 0.76 | — | — | |
| SCHEMBL77751 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023386-A1 | GIP/GLP1 CO-AGONIST COMPOUNDS | ELI LILLY AND COMPANY (US) | 2020-01-30 | — | — | WO | disclosed |
| US-9012398-B2 | Acylated exendin-4 compounds | NOVO NORDISK A/S (DK) | 2015-04-21 | — | — | US | disclosed |
| EP-2057189-B1 | ACYLATED EXENDIN-4 COMPOUNDS | NOVO NORDISK AS (DK) | 2013-03-06 | — | — | EP | disclosed |
| US-20120283170-A1 | Acylated Exendin-4 Compounds | NOVO NORDISK A/S (DK) | 2012-11-08 | — | — | US | disclosed |
| EP-2330126-A1 | Protracted exendin-4 compounds | NOVO NORDISK A/S (DK) | 2011-06-08 | — | — | EP | disclosed |
| US-20090318353-A1 | Acylated Exendin-4 Compounds | NOVO NORDISK A/S (DK) | 2009-12-24 | — | — | US | disclosed |
| WO-2008023050-A1 | ACYLATED EXENDIN-4 COMPOUNDS | NOVO NORDISK A/S (DK) | 2008-02-28 | — | — | WO | disclosed |
| WO-2006097536-A2 | DIMERIC PEPTIDE AGONISTS OF THE GLP-1 RECEPTOR | NOVO NORDISK A/S (DK) | 2006-09-21 | — | — | WO | disclosed |
| WO-2006037811-A2 | PROTRACTED EXENDIN-4 COMPOUNDS | NOVO NORDISK A/S (DK) | 2006-04-13 | — | — | WO | disclosed |