Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.77 |
| ▸ | PPARG | P37231 | 7/20 | 0.77 |
| ▸ | PPARD | Q03181 | 7/20 | 0.77 |
| ▸ | PPARA | Q07869 | 7/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.77 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.77 |
| ▸ | FABP4 | P15090 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | TLR2 | O60603 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.77 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | ESR1 | P03372 | 1/20 | 0.77 |
| ▸ | PDE4A | P27815 | 1/20 | 0.77 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanoic Acid SCHEMBL10478083 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL27680269 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL28252663 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL27658155 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL5510073 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL23856106 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL27885518 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL8725764 | 0.98 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL18825549 | 0.98 | AKR1B1 (0.76) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL27801495 | 0.95 | AKR1B1 (0.73) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110381945-A | The composition of oral gallium (III) complex given | 阿尔图姆制药股份有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-110290835-A | For treating the composition and method of the ophthalmology patient's condition | 麦迪康制药公司 | 2019-09-27 | — | — | CN | claimed |
| CN-109820825-A | It is a kind of for treating the pharmaceutical composition of eye disease | 河北嘉硕生物科技有限公司 | 2019-05-31 | — | — | CN | claimed |
| CN-109718372-A | Carrier and preparation method thereof is immunized in nanoscale emulsion for schneiderian membrance | 财团法人卫生研究院 | 2019-05-07 | — | — | CN | claimed |
| CN-109481445-A | Composition containing morpholine ketone compounds | 黄泳华 | 2019-03-19 | — | — | CN | claimed |
| CN-109473236-A | The manufacturing process of B1 grades of environmentally protective medium-pressure power cables of multistoried building | 江苏亨通电力电缆有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-109430259-A | A kind of pesticide powder and preparation method thereof | 绩溪农华生物科技有限公司 | 2019-03-08 | — | — | CN | claimed |
| CN-109103454-A | Lithium battery graphene conductive slurry and preparation method thereof | 何亚龙 | 2018-12-28 | — | — | CN | claimed |
| CN-108208838-A | A kind of taste masking composition and application thereof | 北京素维生物科技有限公司 | 2018-06-29 | — | — | CN | claimed |
| CN-108085105-A | A kind of continuous casting, and tandem rolling copper rod emulsion and preparation method thereof | 新兴铸管（浙江）铜业有限公司 | 2018-05-29 | — | — | CN | claimed |
| CN-1485025-A | Healthcare whitening cream cosmetics and its production method | 张建忠 | 2004-03-31 | — | — | CN | claimed |
| CN-114867785-B | Vinyl chloride resin composition and molded article | 株式会社可乐丽 | 2024-07-05 | — | — | CN | disclosed |
| US-20240150604-A1 | PRETREATMENT COMPOSITION, PRINT SET, AND TEXTILE PRINTING METHOD | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2024-05-09 | — | — | US | disclosed |
| CN-117940531-A | Chemical additive for improving antifriction agent solution performance and application thereof | 刘飞鹏 | 2024-04-26 | — | — | CN | disclosed |
| US-20240122832-A1 | SUBSTITUTION OF AMMONIA IN HAIR ALTERING PRODUCTS | JEFFERIES FINANCE LLC, AS COLLATERAL AGENT | 2024-04-18 | — | — | US | disclosed |
| US-4349523-A | FROM AN ACRYLONITRILE COPOLYMER HAVING A CATIONIC GROUP, OXIDIZING THE FIBER FOLLOWED BY CARBONIZATION | TORAY INDUSTRIES, INC. (JP) | 1982-09-14 | — | — | US | disclosed |
| US-4259103-A | ADSORPTION ON SUBSTRATE BY ION EXCHANGE | DOW CORNING CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |
| US-4255304-A | DISCOLORATION INHIBITION | AMERICAN CYANAMID COMPANY (US) | 1981-03-10 | — | — | US | disclosed |
| US-4223065-A | POLYSILOXANE, ALKYLOXYALKYL MELAMINE, METAL SALT OF A PHOSPHATE ESTER ANTISTATIC AGENT | UNITIKA LTD (JP) | 1980-09-16 | — | — | US | disclosed |
| US-4071629-A | THIAMINE DISULFIDE DERIVATIVE | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1978-01-31 | — | — | US | disclosed |