Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347781 | 0.85 | POLB (0.60) | POLBLTA4HDRD2DRD3MEN1 | |
| SCHEMBL3645245 | 0.85 | POLB (0.60) | POLBLTA4HDRD2DRD3MEN1 | |
| SCHEMBL8220698 | 0.83 | POLB (0.57) | POLBLTA4HDRD2DRD3SSTR2 | |
| SCHEMBL8269038 | 0.82 | POLB (0.63) | POLBLTA4HDRD2DRD3SCN9A | |
| SCHEMBL10132521 | 0.81 | POLB (0.54) | POLBDRD2DRD3MEN1GAA | |
| SCHEMBL8220385 | 0.79 | POLB (0.52) | POLBLTA4HSSTR2 | |
| SCHEMBL8222114 | 0.79 | LTA4H (0.57) | POLBLTA4HDRD2FFAR1SSTR2 | |
| SCHEMBL10132546 | 0.78 | POLB (0.56) | POLBLTA4HHTR6 | |
| SCHEMBL22456442 | 0.78 | POLB (0.56) | POLBLTA4HHTR6 | |
| SCHEMBL8221615 | 0.76 | POLB (0.51) | POLBSSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |