Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.42 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8205786 | 0.99 | TP53 (0.47) | TP53RORCCHRNA7CNR1CNR2 | |
| SCHEMBL8213939 | 0.87 | NPC1 (0.57) | RORCCHRNA7CNR1CNR2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8213598 | 0.86 | NPC1 (0.56) | RORCCHRNA7CNR1CNR2SMN1; SMN2 | |
| SCHEMBL8206309 | 0.84 | MAPT (0.50) | TP53RORCCHRNA7CNR1CNR2 | |
| SCHEMBL8218668 | 0.84 | NPC1 (0.59) | TP53CHRNA7SMN1; SMN2MAPT | |
| SCHEMBL8214395 | 0.84 | SMN1; SMN2 (0.51) | TP53RORCCHRNA7CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL8212735 | 0.83 | SMN1; SMN2 (0.50) | TP53RORCCHRNA7CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL8214647 | 0.83 | MAPT (0.49) | TP53RORCCHRNA7CNR1CNR2 | |
| SCHEMBL8216078 | 0.83 | MEN1 (0.60) | SMN1; SMN2MAPTLMNA | |
| Hydrochloric Acid SCHEMBL8216489 | 0.83 | NPC1 (0.58) | TP53CHRNA7SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008022-A1 | UREA DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2000-02-17 | — | — | WO | claimed |