Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8216489 | 0.99 | NPC1 (0.58) | NPC1RAB9ACASP3SENP7ALDH1A1 | |
| SCHEMBL8212966 | 0.84 | TP53 (0.48) | MAPTTP53SMN1; SMN2CHRNA7 | |
| SCHEMBL8213939 | 0.84 | NPC1 (0.57) | NPC1RAB9ACASP3SENP7MEN1 | |
| SCHEMBL8214395 | 0.84 | SMN1; SMN2 (0.51) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL8206309 | 0.84 | MAPT (0.50) | NPC1RAB9AMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8213598 | 0.83 | NPC1 (0.56) | NPC1RAB9ACASP3SENP7MEN1 | |
| Hydrochloric Acid SCHEMBL8205786 | 0.83 | TP53 (0.47) | MAPTTP53SMN1; SMN2CHRNA7 | |
| Hydrochloric Acid SCHEMBL8212735 | 0.83 | SMN1; SMN2 (0.50) | NPC1RAB9AMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8214647 | 0.83 | MAPT (0.49) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL8216078 | 0.81 | MEN1 (0.60) | NPC1RAB9AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008022-A1 | UREA DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2000-02-17 | — | — | WO | claimed |
| WO-2000008022-A1 | UREA DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2000-02-17 | — | — | WO | disclosed |