Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218924 | 0.85 | HDAC1 (0.47) | TRPV1CYP2D6CYP3A4TSHRUSP2 | |
| SCHEMBL8227883 | 0.75 | CACNA1H (0.47) | ALDH1A1MAPK1CACNA1H | |
| SCHEMBL8213185 | 0.72 | CACNA1H (0.41) | CACNA1H | |
| SCHEMBL26822130 | 0.71 | MDM2 (0.42) | CACNA1HOPRK1 | |
| SCHEMBL8212405 | 0.70 | CACNA1H (0.71) | TRPV1CACNA1H | |
| SCHEMBL12876984 | 0.70 | CACNA1H (0.71) | TRPV1CACNA1H | |
| SCHEMBL17888237 | 0.69 | HDAC1 (0.54) | MAPK1 | |
| SCHEMBL8224879 | 0.68 | HDAC1 (0.44) | TRPV1TSHROPRK1 | |
| SCHEMBL8208288 | 0.68 | HDAC1 (0.47) | TRPV1TSHR | |
| SCHEMBL8227850 | 0.68 | HDAC1 (0.45) | TRPV1TSHROPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033465-A1 | AZETIDINONE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |