Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221295 | 0.92 | FFAR4 (0.38) | KMOFFAR4DHODHFFAR1SCN5A | |
| SCHEMBL8221375 | 0.90 | KMO (0.43) | KMODHODHSCN5AEIF4EPTGER4 | |
| SCHEMBL3345267 | 0.83 | KMO (0.45) | KMOFFAR4DHODHAKR1C2AKR1C1 | |
| SCHEMBL8217120 | 0.79 | KMO (0.39) | KMOSCN5A | |
| SCHEMBL3340037 | 0.76 | FFAR4 (0.41) | KMOFFAR4DHODHFFAR1SCN5A | |
| SCHEMBL8216214 | 0.76 | KDM4E (0.39) | KMODHODHSCN5ACYP2C9 | |
| SCHEMBL3345443 | 0.72 | KMO (0.44) | KMODHODHSCN5AEIF4EMRGPRX4 | |
| SCHEMBL3342506 | 0.70 | KMO (0.48) | KMOSCN5A | |
| SCHEMBL3339524 | 0.70 | KMO (0.44) | KMODHODHSCN5AEIF4E | |
| SCHEMBL3342587 | 0.69 | KMO (0.47) | KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031500-A1 | 4-PHENOXY-NICOTINE ACID DERIVATIVES AND USE THEREOF AS PPAR-MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-20 | — | — | WO | disclosed |