Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | NPY4R | P50391 | 4/20 | 0.36 |
| ▸ | NPY1R | P25929 | 3/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.34 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814623 | 1.00 | OTC (0.41) | OTCDDAH1DPP7ALOX15MEN1 | |
| SCHEMBL4810722 | 0.87 | DPP7 (0.40) | OTCDDAH1DPP7ALOX15MEN1 | |
| SCHEMBL15820093 | 0.87 | DPP7 (0.40) | OTCDDAH1DPP7ALOX15MEN1 | |
| SCHEMBL4810699 | 0.87 | DPP7 (0.40) | OTCDDAH1DPP7ALOX15MEN1 | |
| Arginine SCHEMBL16194086 | 0.86 | OTC (0.53) | OTCDDAH1ALOX15MEN1CYP1A2 | |
| Arginine SCHEMBL16194085 | 0.86 | OTC (0.53) | OTCDDAH1ALOX15MEN1CYP1A2 | |
| SCHEMBL5492513 | 0.85 | DPP7 (0.41) | OTCDDAH1DPP7ALOX15MEN1 | |
| Arginine SCHEMBL6374054 | 0.85 | OTC (0.56) | OTCDDAH1ALOX15MEN1CYP1A2 | |
| Arginine SCHEMBL288132 | 0.85 | OTC (0.56) | OTCDDAH1ALOX15MEN1CYP1A2 | |
| Arginine SCHEMBL7928810 | 0.85 | OTC (0.56) | OTCDDAH1ALOX15MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916888-A | Imidazo 1,5A!pyridine derived serine protease inhibitors | AKZO NOBEL, N.V. (NL) | 1999-06-29 | — | — | US | claimed |
| EP-0830371-B1 | IMIDAZO(1,5a]PYRIDINE DERIVED SERINE PROTEASE INHIBITORS | AKZO NOBEL NV (NL) | 2000-12-20 | — | — | EP | disclosed |
| US-5916888-A | Imidazo 1,5A!pyridine derived serine protease inhibitors | AKZO NOBEL, N.V. (NL) | 1999-06-29 | — | — | US | disclosed |
| EP-0830371-A1 | IMIDAZO 1,5a]PYRIDINE DERIVED SERINE PROTEASE INHIBITORS | Akzo Nobel N.V. (NL) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996038470-A1 | IMIDAZO[1,5a]PYRIDINE DERIVED SERINE PROTEASE INHIBITORS | AKZO NOBEL N.V. (NL) | 1996-12-05 | — | — | WO | disclosed |