Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | OTC | P00480 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 7/20 | 0.37 |
| ▸ | NPY1R | P25929 | 5/20 | 0.37 |
| ▸ | NPY2R | P49146 | 3/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4810722 | 1.00 | DPP7 (0.40) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL15820093 | 0.89 | DPP7 (0.40) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL8213398 | 0.87 | OTC (0.41) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL11814623 | 0.87 | OTC (0.41) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL4255647 | 0.86 | DPP7 (0.41) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL8745862 | 0.85 | DDAH1 (0.40) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL9190017 | 0.85 | DDAH1 (0.40) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL30256813 | 0.85 | DPP7 (0.42) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL598710 | 0.85 | DPP7 (0.42) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL304115 | 0.85 | DPP7 (0.42) | DPP7OTCALOX15MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9090658-B2 | Base-substituted benzylamine analogs for use as coagulation factor Xa inhibitors, the production and use thereof | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| US-7407982-B2 | Oligo or polyalkylene glycol-coupled thrombin inhibitors | HAEMOSYS GMBH (DE) | 2008-08-05 | — | — | US | disclosed |
| US-20070066539-A1 | Base-substituted benzylamine analogs for use as coagulation factor xa inhibitors, the production and use thereof | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
| US-20050119190-A1 | Inhibitors of the blood-clotting factor xa, production thereof and use of the same | CURACYTE AG (DE) | 2005-06-02 | — | — | US | disclosed |
| US-20050070479-A1 | Oligo or polyalkylene glycol-coupled thrombin inhibitors | HAEMOSYS GMBH (DE) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066539-A1 | Base-substituted benzylamine analogs for use as coagulation factor xa inhibitors, the production and use thereof | F12, F2, F11 | DPP7 1220/4885OTC 2560/4885ALOX15 1550/4885 |
| US-20050119190-A1 | Inhibitors of the blood-clotting factor xa, production thereof and use of the same | SERPINC1, TFPI, F11 | DPP7 349/4885OTC 2502/4885ALOX15 1259/4885 |
| US-20050070479-A1 | Oligo or polyalkylene glycol-coupled thrombin inhibitors | TFPI, SERPINC1, PLG | DPP7 238/4885OTC 1023/4885ALOX15 521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.