Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.81 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.78 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | PPARG | P37231 | 4/20 | 0.61 |
| ▸ | PPARA | Q07869 | 3/20 | 0.61 |
| ▸ | PPARD | Q03181 | 2/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4530820 | 0.92 | FFAR1 (0.88) | FFAR1FFAR4SRD5A2LMNAL3MBTL1 | |
| SCHEMBL2774842 | 0.90 | FFAR1 (1.00) | FFAR1FFAR4SRD5A2 | |
| SCHEMBL1744943 | 0.88 | FFAR1 (1.00) | FFAR1FFAR4SRD5A2 | |
| SCHEMBL1747130 | 0.88 | FFAR1 (1.00) | FFAR1FFAR4SRD5A2 | |
| SCHEMBL1744690 | 0.87 | FFAR1 (1.00) | FFAR1FFAR4LMNAL3MBTL1PPARG | |
| SCHEMBL1746597 | 0.86 | FFAR1 (1.00) | FFAR1FFAR4LMNAL3MBTL1 | |
| SCHEMBL1745370 | 0.85 | FFAR1 (1.00) | FFAR1FFAR4LMNAL3MBTL1 | |
| SCHEMBL5926621 | 0.85 | FFAR1 (0.90) | FFAR1FFAR4SRD5A2 | |
| SCHEMBL11587499 | 0.85 | FFAR4 (0.75) | FFAR1FFAR4PPARALTA4H | |
| Apteniol A SCHEMBL16431559 | 0.85 | FFAR1 (0.89) | FFAR1FFAR4SRD5A2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915994-A1 | CYCLIC AMINE DERIVATIVE CONTAINING PPAR REGULATOR | Sankyo Company, Limited (JP) | 2008-04-30 | — | — | EP | disclosed |
| WO-2008028914-A1 | COMBINATION TREATMENT FOR DIABETES MELLITUS | NYCOMED GMBH (DE) | 2008-03-13 | — | — | WO | disclosed |