Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 1.00 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.74 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.74 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.66 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | PPARD | Q03181 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746597 | 0.95 | FFAR1 (1.00) | FFAR1S1PR1S1PR3FFAR4LMNA | |
| SCHEMBL4656572 | 0.94 | FFAR1 (0.97) | FFAR1S1PR1S1PR3FFAR4LMNA | |
| SCHEMBL1745370 | 0.92 | FFAR1 (1.00) | FFAR1S1PR1S1PR3FFAR4LMNA | |
| SCHEMBL4530820 | 0.92 | FFAR1 (0.88) | FFAR1S1PR1S1PR3FFAR4LMNA | |
| SCHEMBL1746650 | 0.88 | FFAR1 (0.88) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL8213476 | 0.87 | FFAR1 (0.81) | FFAR1FFAR4LMNAL3MBTL1PPARG | |
| SCHEMBL8767174 | 0.87 | FFAR1 (0.79) | FFAR1S1PR1S1PR3FFAR4LMNA | |
| SCHEMBL15890920 | 0.85 | S1PR1 (0.90) | FFAR1S1PR1S1PR3S1PR5 | |
| SCHEMBL12916840 | 0.85 | FFAR1 (0.74) | FFAR1S1PR1S1PR3FFAR4S1PR5 | |
| SCHEMBL949867 | 0.85 | S1PR1 (1.00) | FFAR1S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1559422-B1 | RECEPTOR FUNCTION CONTROLLING AGENT | TAKEDA PHARMACEUTICAL (JP) | 2014-04-30 | — | — | EP | disclosed |
| EP-2385032-A1 | GPR40 Receptor function regulator | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20090012093-A1 | Receptor Function Regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1559422-A1 | RECEPTOR FUNCTION CONTROLLING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012093-A1 | Receptor Function Regulator | GPR119, GIPR, INSR | FFAR1 33/4885S1PR1 923/4885S1PR3 1064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.