Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228328 | 0.77 | LMNA (0.37) | AKR1C1LMNAALDH1A1CES2CES1 | |
| SCHEMBL6692163 | 0.75 | AKR1C1 (0.45) | AKR1C1LMNAALDH1A1CES2CES1 | |
| SCHEMBL27279 | 0.73 | HDAC4 (0.46) | AKR1C1LMNAALDH1A1CES2CES1 | |
| Benzene SCHEMBL29067363 | 0.73 | HDAC4 (0.46) | AKR1C1LMNAALDH1A1CES2CES1 | |
| SCHEMBL28231289 | 0.73 | HDAC4 (0.46) | AKR1C1LMNAALDH1A1CES2CES1 | |
| SCHEMBL6695613 | 0.73 | HDAC4 (0.46) | AKR1C1LMNAALDH1A1CES2CES1 | |
| Water SCHEMBL29044078 | 0.72 | HDAC4 (0.44) | AKR1C1LMNAALDH1A1CES2CES1 | |
| SCHEMBL8529984 | 0.71 | AKR1C1 (0.45) | AKR1C1LMNAALDH1A1CES2CES1 | |
| SCHEMBL9224136 | 0.71 | FASN (0.45) | AKR1C1LMNAALDH1A1CES2CES1 | |
| SCHEMBL29155399 | 0.71 | AKR1C1 (0.45) | AKR1C1LMNAALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048667-A | FREE RADICALS OR CATION POLYMERIZABLE OR PHOTOCROSSLINKABLE MONOMERS, SUBSTRATES AND PHOTOINITIATORS, BONDING WITH SUBSTRATES | CIBA SPECIALTY CHEMICALS CORP. (US) | 2000-04-11 | — | — | US | disclosed |