Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL821358 | 1.00 | KDR (0.60) | KDRCYP1A2CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL821342 | 0.91 | KDR (0.49) | KDRCYP1A2SMN1; SMN2 | |
| SCHEMBL20377156 | 0.91 | KDR (0.49) | KDRCYP1A2SMN1; SMN2 | |
| SCHEMBL810845 | 0.87 | KDR (0.44) | KDRCYP1A2CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL810844 | 0.87 | KDR (0.44) | KDRCYP1A2CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL17038721 | 0.85 | KDR (0.73) | KDRSMN1; SMN2 | |
| SCHEMBL29356197 | 0.85 | KDR (0.73) | KDRSMN1; SMN2 | |
| SCHEMBL29482612 | 0.84 | KDR (0.68) | KDRTSHRSMN1; SMN2 | |
| SCHEMBL2360954 | 0.84 | KDR (0.68) | KDRTSHRSMN1; SMN2 | |
| SCHEMBL2360952 | 0.84 | KDR (0.68) | KDRTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399569-B1 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | HENKEL AG & CO KGAA (DE) | 2018-07-18 | — | — | EP | claimed |
| EP-2399569-A2 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | Henkel AG & Co. KGaA (DE) | 2011-12-28 | — | — | EP | claimed |
| EP-2399569-B1 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | HENKEL AG & CO KGAA (DE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2399569-A2 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | Henkel AG & Co. KGaA (DE) | 2011-12-28 | — | — | EP | disclosed |