Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20377156 | 1.00 | KDR (0.49) | KDRKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL821359 | 0.91 | KDR (0.60) | KDRCYP1A2SMN1; SMN2 | |
| SCHEMBL821358 | 0.91 | KDR (0.60) | KDRCYP1A2SMN1; SMN2 | |
| SCHEMBL810844 | 0.86 | KDR (0.44) | KDRKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL810845 | 0.86 | KDR (0.44) | KDRKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL23695700 | 0.86 | KDR (0.57) | KDRKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL821531 | 0.83 | MEN1 (0.38) | ALDH1A1LMNACYP1A2MAPTCYP2C19 | |
| SCHEMBL821530 | 0.83 | MEN1 (0.38) | ALDH1A1LMNACYP1A2MAPTCYP2C19 | |
| SCHEMBL821710 | 0.82 | RIPK1 (0.35) | KDRALDH1A1CYP1A2MAPTCYP2C9 | |
| SCHEMBL20377114 | 0.82 | RIPK1 (0.35) | KDRALDH1A1CYP1A2MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399569-B1 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | HENKEL AG & CO KGAA (DE) | 2018-07-18 | — | — | EP | claimed |
| EP-2399569-A2 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | Henkel AG & Co. KGaA (DE) | 2011-12-28 | — | — | EP | claimed |
| EP-2399569-B1 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | HENKEL AG & CO KGAA (DE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2399569-A2 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | Henkel AG & Co. KGaA (DE) | 2011-12-28 | — | — | EP | disclosed |