Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27357965 | 0.88 | TLR8 (0.49) | TLR8ALDH1A1MAPTHPGDGLA | |
| SCHEMBL8672800 | 0.82 | TLR8 (0.49) | TLR8ALDH1A1MAPTHPGDGLA | |
| SCHEMBL6535908 | 0.81 | TLR8 (0.48) | TLR8ALDH1A1MAPTHPGDGLA | |
| SCHEMBL2818584 | 0.81 | TLR8 (0.68) | TLR8ALDH1A1MAPTHPGDGLA | |
| SCHEMBL28237515 | 0.81 | KMT2A (0.42) | TLR8ALDH1A1MAPTHPGDGLA | |
| SCHEMBL9242375 | 0.81 | TLR8 (0.48) | TLR8ALDH1A1MAPTHPGDGLA | |
| SCHEMBL7191719 | 0.81 | TLR8 (0.48) | TLR8ALDH1A1MAPTHPGDGLA | |
| SCHEMBL1115863 | 0.81 | ALDH1A1 (0.49) | TLR8ALDH1A1MAPTHPGDGLA | |
| SCHEMBL27812919 | 0.81 | ALDH1A1 (0.42) | TLR8ALDH1A1MAPTHPGDGLA | |
| Hydrochloric Acid SCHEMBL5480918 | 0.79 | TLR8 (0.66) | TLR8ALDH1A1MAPTHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103904-A | Skraup reaction process for synthesizing quinolones | BASF CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0398967-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-11-28 | — | — | EP | disclosed |
| WO-1989006649-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-07-27 | — | — | WO | disclosed |