Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 3/20 | 0.38 |
| ▸ | CPA1 | P15085 | 3/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261968 | 0.90 | NAALAD2 (0.45) | ACEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7893068 | 0.89 | HDAC3 (0.45) | ACEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7258341 | 0.89 | HDAC3 (0.44) | ACEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7262993 | 0.88 | NAALAD2 (0.45) | ACEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7258311 | 0.82 | BCHE (0.44) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL7263044 | 0.82 | HDAC3 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7257322 | 0.81 | HDAC3 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7261630 | 0.81 | BCHE (0.44) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL9234429 | 0.77 | HDAC3 (0.39) | ACEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7900190 | 0.77 | FOLH1 (0.41) | ACEHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140100-A | CONJUGATE POLYPEPTIDE WHICH IS TISSUE PREFERENTIAL; ANTICARCINOGENIC AGENTS | GLAXO WELLCOME INC. (US) | 2000-10-31 | — | — | US | disclosed |