SCHEMBL821404

SCHEMBL821404

CCCCCN1/C(=C/C=C2/C(Cl)=C(/C=C/C3=[N+](CCCCC)c4ccc5cc(Br)ccc5c4C3(C)C)c3ccccc32)C(C)(C)c2c1ccc1cc(Br)ccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 13/20 0.54
BLM P54132 1/20 0.48
PRMT5 O14744 2/20 0.47
PRMT8 Q9NR22 2/20 0.47
MLNR O43193 1/20 0.46
NR1I2 O75469 1/20 0.46
PGR P06401 1/20 0.46
ADRB1 P08588 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CHRM1 P11229 1/20 0.46
DRD2 P14416 1/20 0.46
ADRA2B P18089 1/20 0.46
ADRA2C P18825 1/20 0.46
CHRM3 P20309 1/20 0.46
CNR1 P21554 1/20 0.46
DRD1 P21728 1/20 0.46
TBXA2R P21731 1/20 0.46
SLC6A2 P23975 1/20 0.46
HRH2 P25021 1/20 0.46
HTR2C P28335 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821463 0.94 MLNR (0.55) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL822090 0.93 PRMT1 (0.49) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL821558 0.92 PRMT1 (0.55) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL821744 0.91 PRMT1 (0.54) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL821439 0.91 PRMT1 (0.53) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL821819 0.90 PRMT1 (0.56) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL821421 0.90 PRMT1 (0.52) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL821153 0.89 PRMT1 (0.52) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL822089 0.88 PRMT1 (0.51) PRMT1BLMPRMT5PRMT8MLNR
SCHEMBL17348223 0.88 PRMT1 (0.70) PRMT1BLMPRMT5PRMT8MLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8778590-B2 Lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2014-07-15 US disclosed
US-8632950-B2 Cyanine dyes and lithographic printing plate precursors comprising such dyes AGFA GRAPHICS NV (BE) 2014-01-21 US disclosed
US-20120208126-A1 NOVEL CYANINE DYES AND LITHOGRAPHIC PRINTING PLATE PRECURSORS COMPRISING SUCH DYES AGFA GRAPHICS NV (BE) 2012-08-16 US disclosed
US-20110287364-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2011-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208126-A1 NOVEL CYANINE DYES AND LITHOGRAPHIC PRINTING PLATE PRECURSORS COMPRISING SUCH DYES LCP1, MLN, PRCP PRMT1 1891/4885BLM 4444/4885PRMT5 1113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.