Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.62 |
| ▸ | BCL2 | P10415 | 15/20 | 0.57 |
| ▸ | BAK1 | Q16611 | 6/20 | 0.57 |
| ▸ | BCL2L1 | Q07817 | 10/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1956895 | 0.92 | HTR7 (0.74) | HTR7BCL2BAK1BCL2L1 | |
| SCHEMBL29846744 | 0.88 | BCL2 (0.71) | HTR7BCL2BAK1BCL2L1 | |
| SCHEMBL1741405 | 0.88 | BCL2 (0.71) | HTR7BCL2BAK1BCL2L1 | |
| SCHEMBL26682055 | 0.82 | HTR7 (0.60) | HTR7BCL2BAK1BCL2L1 | |
| SCHEMBL19014872 | 0.82 | BCL2 (0.62) | BCL2BAK1BCL2L1 | |
| SCHEMBL26683082 | 0.79 | HTR7 (0.53) | HTR7BCL2BAK1BCL2L1 | |
| SCHEMBL20778266 | 0.78 | BCL2 (0.70) | HTR7BCL2BAK1BCL2L1 | |
| SCHEMBL30688260 | 0.78 | BCL2 (0.70) | HTR7BCL2BAK1BCL2L1 | |
| SCHEMBL27688816 | 0.78 | HRH3 (0.52) | HTR7BCL2BAK1 | |
| SCHEMBL15938148 | 0.78 | HTR7 (1.00) | HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033747-A9 | MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS | CURIS INC (MA) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008033747-A2 | MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS | CURIS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |