Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8214205 | 1.00 | SRC (0.39) | SRCABCB1TACR1MEN1KMT2A | |
| SCHEMBL8789793 | 0.91 | SRC (0.46) | SRCABCB1TACR1MEN1KMT2A | |
| SCHEMBL5404919 | 0.91 | SRC (0.46) | SRCABCB1TACR1MEN1KMT2A | |
| SCHEMBL5409336 | 0.88 | SRC (0.40) | SRCABCB1TACR1NR1H2NR1H3 | |
| SCHEMBL5406636 | 0.84 | HCRTR2 (0.41) | SRCNR1H2NR1H3HSD11B1JAK2 | |
| SCHEMBL8201900 | 0.82 | GPR119 (0.39) | ABCB1TACR1MEN1KMT2ARORC | |
| SCHEMBL9034741 | 0.82 | GPR119 (0.39) | ABCB1TACR1MEN1KMT2ARORC | |
| SCHEMBL8211858 | 0.82 | GPR119 (0.39) | ABCB1TACR1MEN1KMT2ARORC | |
| SCHEMBL8390205 | 0.82 | GPR119 (0.39) | ABCB1TACR1MEN1KMT2ARORC | |
| SCHEMBL5492058 | 0.81 | HTRA1 (0.41) | ABCB1KMT2ANR1H2NR1H3RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054865-A1 | FARNESYL TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041235-A1 | FARNESYL TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |