Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.36 |
| ▸ | FNTA | P49354 | 3/20 | 0.34 |
| ▸ | FNTB | P49356 | 3/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199296 | 0.92 | NAMPT (0.38) | NAMPTFNTAFNTBPGGT1B | |
| SCHEMBL8209424 | 0.90 | FNTA (0.43) | FNTAFNTB | |
| SCHEMBL8233409 | 0.84 | CYP51A1 (0.41) | FNTAFNTBPGGT1B | |
| SCHEMBL8198171 | 0.83 | FNTA (0.34) | NAMPTFNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL8209899 | 0.83 | FNTA (0.40) | FNTAFNTB | |
| SCHEMBL8199776 | 0.83 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL8206519 | 0.82 | NAMPT (0.38) | NAMPTFNTAFNTBPGGT1B | |
| SCHEMBL8199442 | 0.82 | FNTA (0.39) | NAMPTFNTAFNTBPGGT1B | |
| SCHEMBL8207254 | 0.82 | FNTA (0.47) | FNTAFNTB | |
| SCHEMBL8207389 | 0.80 | FNTA (0.40) | NAMPTFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054865-A1 | FARNESYL TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-11-29 | — | — | EP | claimed |
| WO-1999041235-A1 | FARNESYL TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | claimed |