Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199296 | 0.88 | NAMPT (0.38) | NAMPTFNTAFNTBPGGT1B | |
| SCHEMBL8207254 | 0.88 | FNTA (0.47) | FNTAFNTB | |
| SCHEMBL8207389 | 0.88 | FNTA (0.40) | NAMPTFNTAFNTBPGGT1B | |
| SCHEMBL8199776 | 0.86 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL8213603 | 0.86 | HTR2B (0.40) | NAMPT | |
| SCHEMBL8213729 | 0.85 | FNTA (0.37) | NAMPTFNTAFNTB | |
| SCHEMBL8199442 | 0.84 | FNTA (0.39) | NAMPTFNTAFNTBPGGT1B | |
| SCHEMBL8198655 | 0.84 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL8214271 | 0.82 | NAMPT (0.36) | NAMPTFNTAFNTBPGGT1B | |
| SCHEMBL8209424 | 0.82 | FNTA (0.43) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | claimed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | claimed |
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |