Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8214518 | 1.00 | RARB (0.56) | RARBTP53TSHRPLA2G4BS1PR1 | |
| SCHEMBL8214349 | 1.00 | RARB (0.56) | RARBTP53TSHRPLA2G4BS1PR1 | |
| SCHEMBL8216185 | 0.99 | RARB (0.54) | RARBTP53TSHRPLA2G4BS1PR1 | |
| SCHEMBL8220584 | 0.96 | RARB (0.50) | RARBTP53TSHRPLA2G4B | |
| SCHEMBL8217238 | 0.91 | LMNA (0.49) | RARB | |
| SCHEMBL1667028 | 0.87 | TP53 (0.57) | RARBTP53TSHRPLA2G4BS1PR1 | |
| SCHEMBL1667029 | 0.87 | TP53 (0.57) | RARBTP53TSHRPLA2G4BS1PR1 | |
| SCHEMBL8208890 | 0.85 | RARB (0.57) | RARB | |
| SCHEMBL8219844 | 0.83 | RARB (0.56) | RARB | |
| SCHEMBL8207836 | 0.79 | MCL1 (0.46) | RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6106908-A | OPTICAL APPARATUS WITH LIQUID CRYSTAL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 2000-08-22 | — | — | US | disclosed |