Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18775073 | 0.84 | ALDH1A1 (0.36) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18872255 | 0.83 | SMN1; SMN2 (0.36) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16075552 | 0.77 | MAPT (0.41) | ALDH1A1KMT2ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL16975531 | 0.77 | MEN1 (0.42) | ALDH1A1GAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL9921756 | 0.76 | ALDH1A1 (0.38) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17393082 | 0.76 | ALDH1A1 (0.38) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17486664 | 0.75 | MAPT (0.40) | ALDH1A1KMT2ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL5839782 | 0.74 | ALDH1A1 (0.37) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16975487 | 0.74 | ALDH1A1 (0.41) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6893345 | 0.74 | ALDH1A1 (0.41) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6027777-A | FOR FABRICATION OF APPLIANCES FOR FIXING, SUPPORTING, CORRECTING, HOLDING HUMAN BODIES, CHARACTERIZED BY A MAIN FORMING MATERIAL BODY INCLUDING GRANULATED MATERIALS COATED WITH MOISTURE-CURABLE URETHANE PREPOLYMER; MEDICAL EQUIPMENT | ALCARE CO. LTD. (JP) | 2000-02-22 | — | — | US | disclosed |