SCHEMBL8214902

SCHEMBL8214902

NC1CCCN(c2ccc(N3CC(CNC(=O)c4ccc(Cl)s4)CC3=O)cc2F)C1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8238980 0.87 F10 (0.76) F10
SCHEMBL87244 0.87 F10 (1.00) F10
SCHEMBL8240339 0.86 F10 (0.77) F10
SCHEMBL8248614 0.85 F10 (0.77) F10
SCHEMBL13479666 0.85 F10 (0.80) F10
SCHEMBL8247057 0.85 F10 (0.62) F10
SCHEMBL13479694 0.83 F10 (0.61) F10
SCHEMBL87018 0.82 F10 (1.00) F10
SCHEMBL13225527 0.82 F10 (1.00) F10
SCHEMBL8248467 0.81 F10 (0.74) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008052671-A2 COMBINATION THERAPY OF SUBSTITUTED OXAZOLIDINONES BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-05-08 WO disclosed