SCHEMBL8240339

SCHEMBL8240339

O=C(NC[C@@H]1CC(=O)N(c2ccc(N3CCOCC3)c(F)c2)C1)c1ccc(Cl)s1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8238980 0.91 F10 (0.76) F10
SCHEMBL5482932 0.89 F10 (0.72) F10
SCHEMBL8248614 0.89 F10 (0.77) F10
SCHEMBL8247057 0.88 F10 (0.62) F10
SCHEMBL77206 0.87 F10 (1.00) F10
SCHEMBL8214902 0.86 F10 (0.76) F10
SCHEMBL13263368 0.83 MAOB (0.72) F10
SCHEMBL8108062 0.82 F10 (0.56) F10
SCHEMBL13977416 0.82 F10 (0.74) F10
SCHEMBL8101662 0.82 F10 (0.74) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1411932-B1 SUBSTITUTED OXAZOLIDINONES FOR COMBINATIONAL THERAPY BAYER SCHERING PHARMA AG (DE) 2010-02-10 EP disclosed
WO-2007042146-A1 MICROANGIOPATHY TREATMENT AND PREVENTION BAYER HEALTHCARE AG (DE) 2007-04-19 WO disclosed
WO-2007039134-A1 COMBINATION THERAPY COMPRISING SUBSTITUTED OXAZOLIDINONES FOR THE PREVENTION AND TREATMENT OF CEREBRAL CIRCULATORY DISORDERS BAYER HEALTHCARE AG (DE) 2007-04-12 WO disclosed
WO-2003000256-A1 SUBSTITUTED OXAZOLIDINONES FOR COMBINATIONAL THERAPY BAYER HEALTHCARE AG (DE) 2003-01-03 WO disclosed